Calming Turbulent Seas The Therapeutic Effects of CBD for Nausea and Vomiting

Throughout centuries, physicians and folk medicine practitioners have been puzzled by the phenomenon of nausea. In the quest to eliminate this uncomfortable physical symptom, a myriad of tinctures, pharmaceuticals and breathing techniques have been recommended. However, many remedies are only effective at treating specific causes of nausea. For example, those who get motion sickness are often given dimenhydrinate, also known as Dramamine. Although these treatments may be effective, is it possible to treat the biological causes of nausea and vomiting without the use of pharmaceuticals?

For decades, scientists have asked themselves this very question. While many theories have accumulated over the years, the recent uptick in research within the realm of cannabinoids may hold the key to decoding this very human experience. And what is this answer? You may be surprised.

Cannabidiol (CBD) – A Fundamental Understanding

Cannabis is an enigma for many. While tens of thousands of research studies have attempted to further the understanding of this ancient herb, we’re still within the infancy of fully grasping its capabilities as a medicinal compound. The majority of studies have focused on the popular cannabinoid, THC (tetrahydrocannabinol), which is the compound responsible for the getting users “stoned.” However, another cannabinoid is showing greater promise when it comes to medicinal uses – CBD (cannabidiol).

Unlike THC and other related cannabinoids, CBD doesn’t appear to bind to either CB-1 or CB-2 receptor sites (1). Instead, its medicinal qualities may be caused by supporting a natural (endogenous) cannabinoid enzyme, known as anandamide.

The February 2013 edition of the British Journal of Clinical Pharmacology suggests the medicinal use of CBD can potentially (2):

  • Suppress seizures
  • Reduce severity of inflammatory diseases/disorders
  • Protect neurological activity by warding off neurodegenerative disorders
  • Reduce severity of depression and anxiety

However, one of the more interesting therapeutic effects of CBD is its antiemetic, or anti-nausea/vomiting, abilities.

The Cannabinoid Cure – Soothing Nausea and Vomiting

Although annoying, and sometimes detrimental, the biological causes of nausea and vomiting play an important role in the progression of many species. Classified as a defensive action, the sole purpose of this response is to inhibit the digestion of toxic compounds. Since the discovery of the human endocannabinoid system (ECS), researchers have found this complex network of cannabinoid receptor sites plays a direct role in regulating both nausea and vomiting (3).

Preliminary findings suggest the introduction of CBD indirectly activates a unique compound known as 5-hydroxytryptamiine-1A (5-HT1A). Through a complex biological symphony, the activation of this monoamine neurotransmitter significantly reduces the sensation of nausea and its subsequent vomiting reflex (4). Because of such activity, researchers have found cannabis significantly reduces nausea and vomiting due to chemotherapy and other pharmacological treatments. In fact, studies have found the effects of cannabis to treat these symptoms is even more potent than many modern medicines (3).

Since CBD supports high levels of anandamide by inhibiting fatty acid enzymes responsible for degrading this compound, it’s believed its anti-nausea effects are partially due to the prolonged activation of CB-1 receptors within the brain (3).

As you can see, the ability to reduce nausea and vomiting through therapeutic doses of CBD is quite promising. By interacting with multiple biological processes, cannabis may be the key for those experiencing such symptoms. While we must expand our understanding of marijuana, and delve deeper into its interactions with the human body, what we do know is transforming the way we approach health and healing.



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Bob Wilcox

Bob Wilcox has represented CAT Scientific’s family of homogenizers, magnetic stirrers, liquid handling and related laboratory equipment since 2002 when Staufen, Germany-based CAT Ingenieurbüro M. Zipperer GMbH established operations in North America. Bob oversees CAT Scientific laboratory apparatus sales and service organization from the company’s headquarters in Paso Robles, CA. He also is in charge of the parent company’s line of JetCat jet turbines, turboprop, and helicopter power plants for hobbyists’ radio controlled fixed wing and helicopter model aircraft. -- Earlier in Bob’s career he was involved in visual and special effects as well as camera and electronics supervisory responsibilities for the motion picture and television industry.


  1. Rosie Beckett on September 9, 2017 at 9:08 am

    I had no idea that CBD could potentially suppress seizures. It would be great for more individuals to know this so that they can consult their doctor to see if they should try CBD. That way they can hopefully find something that will actually help with their problems. And, if it possibly helps with depression and anxiety as well, that would be so wonderful for individuals!

  2. CBD Oil Pharma on September 15, 2017 at 5:28 am

    It is not just for seizures, CBD products are great to complement other chronic condition treatments. If we are talking about cancer recent studies have shown that CBD helps your body against cancerogenous cells and sor of hold them back. But the mis important of all, CBD cease the pain of those who have to go under such aggressive treatments.
    More studies about CBD must be done and we have to help make some changes in current laws.

    • Kitty on April 14, 2018 at 3:15 pm

      I wish i knew where to purchase high grade and high milligrams CBD oil. I was diagnosed with multiple chronic conditions 6+ years ago and I’m struggling. Life is not worth living under these conditions.

  3. Lillian Schaeffer on September 24, 2017 at 10:13 am

    It’s interesting that CBD can potentially suppress seizures. My mom has a condition that makes her prone to seizures, and it can be scary. I wonder if we could talk to a professional about CBD to see if that could be beneficial for her.

  4. Actech on October 6, 2017 at 10:52 am

    My oncologist recommended CBD to reduce the nausea from chemo. So far it has enabled me to gain weight and reduce pain.

  5. Jaque Christo on November 22, 2017 at 6:59 am

    Thank you for the therapeutic effects of CBD on nausea and vomiting. I think it’s amazing the potential of CBD, even the ability to help suppress seizures is astounding. I wonder if it would have an effect on chronic migraines. I’ll have to see if any studies have been done, Thank you again for the information.

  6. patricia landry on November 28, 2017 at 5:58 pm

    my husband since taking the tincture oil (cbd) only 2 drops in the am and 2 in the evening he has become very nauseated and can’t stomach food
    i will be stopping it as of tonight. He was taking CBD OIL 4 mg a day and it was helping him temendously but had to stop because we just don’t have
    the money ( $ 206 a month) he never got nauseated . must be something in the tincture oil that is making him sick.

    • Corrine on February 12, 2018 at 10:42 am

      Patricia Landry, in which country do you reside? Have you searched online availability? What about getting it from a different country? What about insurance? Will they cover any portion? My heart breaks for your husband. I know how cbd oil has helped me with my severe pain. I have managed to drop two of my three narcotics and one of the narcotics I have dropped by over 80%! It is heartbreaking to know there is a great medication that is readily available but priced so highly it is out of reach for the average person. I am hoping once it becomes legalized nationally here in Canada the prices will drop. My best to you and your husband, Ms. Landry.

  7. Komal Sharma on April 9, 2018 at 1:52 pm

    Loved the writing style.

  8. Debbi on May 7, 2018 at 6:00 am

    I suffer with chronic nausea. Can u pls tell me where the best place is to buy CBD oil. The strength I shd use & how much pls. I can’t go on like this. It’s been 19 yrs now x

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